Abortion rights advocates secured victories in seven states Tuesday while suffering defeats in three others, as voters across America continued to reshape reproductive rights in the post-Roe landscape during a pivotal election night.

Missouri emerged as a potential watershed moment, with voters clearing the path to overturn one of the nation’s strictest abortion bans. The state could become the first to undo a complete prohibition since the Supreme Court’s 2022 Roe v. Wade reversal. The approved measure would allow restrictions only after fetal viability, typically around 21 weeks.

“Today, Missourians made history and sent a clear message: decisions around pregnancy, including abortion, birth control, and miscarriage care are personal and private,” said Rachel Sweet, campaign manager of Missourians for Constitutional Freedom.

However, abortion opponents scored their first post-Roe ballot victories in Florida, Nebraska, and South Dakota. Florida’s measure fell short of the required 60% supermajority, cementing the state’s six-week ban and dramatically altering abortion access across the South. The outcome represented a significant victory for Governor Ron DeSantis, who directed substantial Republican resources to defeat the initiative.

“A momentous victory for life in Florida and for our entire country,” declared Marjorie Dannenfelser, president of SBA Pro-Life America, praising DeSantis’s leadership in opposing the measure.

Voters approved protective measures in Arizona, Colorado, Maryland, and Montana, while Nevada passed an amendment requiring a second approval in 2026. New York voters endorsed a measure banning discrimination based on “pregnancy outcomes.”

The mixed results coincided with Donald Trump’s presidential victory, adding complexity to the national abortion debate. AP VoteCast found abortion policy significantly influenced voters, with about one-fourth citing it as their most important factor and nearly half calling it important but not primary.

The night brought sweeping changes across multiple states. Arizona’s amendment replaced a 15-week ban with a viability standard, while Colorado expanded access by removing state funding restrictions. Maryland and Montana constitutionally protected existing rights, as South Dakota rejected a 12-week provision and Nebraska adopted measures allowing more restrictions.

The results ended abortion rights advocates’ previous winning streak on statewide ballots since Roe’s fall. Currently, 13 states enforce complete bans with limited exceptions, while four others restrict abortion after approximately six weeks.

Despite strict bans, national abortion rates have slightly increased through medication options and organized travel assistance, though advocates emphasize reduced access particularly affects lower-income and minority residents in restrictive states.

“The reality is a majority of Floridians just voted to end Florida’s abortion ban,” said Lauren Brenzel, campaign director for Yes on 4, highlighting how state-specific voting requirements can override majority support. The defeat transforms Florida from a regional access point to a restrictive state, forcing residents to travel hundreds of miles to reach states with fewer restrictions.